Laroche M, Redon-Dumolard A, Mazieres B, Bernard J
Rheumatology Department, Rangueil Teaching Hospital, Toulouse, France.
Rev Rhum Engl Ed. 1997 Feb;64(2):106-11.
X-ray absorptiometry (Lunar DPX) was performed before and after treatment to determine bone mineral content and density, as well as fat-free mass and body fat, in 28 males and 11 females with a mean age of 37 years who met Doury's criteria for reflex sympathetic dystrophy syndrome. Mean disease duration was eight months. Before treatment, as compared to the unaffected limb, bone mineral content was decreased by 8.8%, bone mineral density by 9.6%, and fat-free mass by 6.2%, whereas body fat was increased by 6%. These differences were largest in those patients with the longest disease durations. The severity of bone loss was not correlated with the outcome, the severity of roentgenographic lesions, or whether the patient was evaluated at the warm or cold stage of the disease process. Study parameters were unchanged after three months both in patients who were and were not improved. After nine to 12 months, increases in bone and fat-free mass were seen in those patients whose clinical manifestations had subsided.
对符合杜里反射性交感神经营养不良综合征标准、平均年龄37岁的28名男性和11名女性,在治疗前后进行双能X线吸收测定法(Lunar DPX),以确定骨矿物质含量和密度,以及去脂体重和体脂。平均病程为8个月。治疗前,与未受影响的肢体相比,骨矿物质含量降低了8.8%,骨矿物质密度降低了9.6%,去脂体重降低了6.2%,而体脂增加了6%。这些差异在病程最长的患者中最为明显。骨质流失的严重程度与治疗结果、X线病变的严重程度,或患者是在疾病过程的热阶段还是冷阶段接受评估均无关。在病情改善和未改善的患者中,3个月后研究参数均未改变。9至12个月后,临床表现消退的患者出现了骨量和去脂体重的增加。