基因疗法。未来已经到来了吗？
Gene therapy. Is the future here yet?
作者信息
Yaron Y, Kramer R L, Johnson M P, Evans M I
机构信息
Department of Obstetrics and Gynecology, Hutzel Hospital, Wayne State University, Detroit, Michigan, USA.
出版信息
Obstet Gynecol Clin North Am. 1997 Mar;24(1):179-99. doi: 10.1016/s0889-8545(05)70296-5.
Despite the overwhelming number of articles on gene therapy that have been published in the last few years, there is a paucity of trials that have successfully demonstrated the clinical usefulness of this modality. The enthusiasm characterizing some of the earlier studies has given way to a more realistic approach. The next step is to develop more efficient vectors for effective targeting and persistent gene expression.
尽管在过去几年里发表了大量关于基因治疗的文章，但成功证明这种治疗方式临床实用性的试验却很少。早期一些研究的热情已被更现实的方法所取代。下一步是开发更有效的载体，以实现有效靶向和持续的基因表达。
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