Tottori J, Yamaguchi R, Murakawa Y, Sato M, Uchida K, Tateyama S
Faculty of Agriculture, Miyazaki University, Japan.
Avian Dis. 1997 Jan-Mar;41(1):214-20.
Common commercial strain male broilers were intratracheally inoculated with 0.3 ml of fluid containing 10(3.7) embryo infective doses of infectious bronchitis virus (IBV) at 14 days of age and 7.5 x 10(6) colony-forming units of Escherichia coli at 18 days of age. Ascites was detected in 15 out of 100 infected birds, which was significantly higher than in a control group of 100 mock-infected birds (P < 0.01). Some parabronchi were blocked by copious exudate containing heterophils and fibrin in the infected birds at 22 days of age although these findings were not seen in the infected birds at 35 days of age or in birds with ascites. The erythrocyte packed cell volume and right ventricle/total ventricle (RV/TV) ratio of birds with ascites were higher than in birds without ascites. The RV/TV weight ratio for the infected group at the age of 35 days was higher than that of the control group. No IBV or E. coli were recovered from the ascitic birds. These findings suggest that these infectious agents induce ascites in the broilers, and then disappear until the birds suffer from ascites.
普通商业品系雄性肉鸡在14日龄时经气管接种0.3毫升含有10(3.7)个胚胎感染剂量传染性支气管炎病毒（IBV）的液体，在18日龄时接种7.5×10(6)个大肠杆菌菌落形成单位。在100只感染鸡中，有15只检测到腹水，这显著高于100只假感染对照鸡（P<0.01）。在22日龄的感染鸡中，一些副支气管被含有嗜异性粒细胞和纤维蛋白的大量渗出物阻塞，不过在35日龄的感染鸡或有腹水的鸡中未见到这些现象。有腹水的鸡的红细胞压积和右心室/总心室（RV/TV）比值高于无腹水的鸡。35日龄感染组的RV/TV重量比高于对照组。在有腹水的鸡中未分离到IBV或大肠杆菌。这些发现表明，这些感染因子在肉鸡中诱发腹水，然后直至鸡出现腹水时消失。
