Rohwedel J, Weichenhan D, Meier C, Traut W
Institut für Biologie, Medizinische Universität zu Lübeck, Germany.
Insect Mol Biol. 1993;2(1):49-58. doi: 10.1111/j.1365-2583.1993.tb00125.x.
Only a few prominent simple sequence repeat (SSR) loci of the type (GATA)n are found in the genome of the mealmoth Ephestia kuehniella Zeller. Therefore this moth was chosen as a model organism for the genetic and molecular analysis of hypervariability of SSR loci. We characterized alleles of (GATA)n loci in different Ephestia strains by cloning and genomic restriction mapping. Some variants appeared to be mere variable number of tandem repeat (VNTR) alleles, others showed considerable changes in the sequence neighbourhood of the GATA repeats. These may be produced by major rearrangements or by transposition of the (GATA)n block together with flanking sequences into a different sequence environment.
在粉斑螟（Ephestia kuehniella Zeller）的基因组中，仅发现了少数几个显著的（GATA）n类型的简单序列重复（SSR）位点。因此，这种蛾被选为用于SSR位点高变异性遗传和分子分析的模式生物。我们通过克隆和基因组限制酶切图谱分析，对不同粉斑螟品系中（GATA）n位点的等位基因进行了表征。一些变异似乎只是串联重复可变数目（VNTR）等位基因，而其他变异则显示出GATA重复序列邻域的序列有相当大的变化。这些可能是由主要重排或（GATA）n片段连同侧翼序列转座到不同的序列环境中产生的。
