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皮肤细胞性纤维组织细胞瘤:与皮肤纤维肉瘤不同核型的克隆性过程的证据。

Cellular fibrous histiocytoma of the skin: evidence of a clonal process with different karyotype from dermatofibrosarcoma.

作者信息

Vanni R, Marras S, Faa G, Licheri S, Daniele G M, Fletcher C D

机构信息

Istituto di Biologia Generale, University of Cagliari, Italy.

出版信息

Genes Chromosomes Cancer. 1997 Apr;18(4):314-7. doi: 10.1002/(sici)1098-2264(199704)18:4<314::aid-gcc11>3.0.co;2-g.

Abstract

Recently, a distinct variant of cutaneous fibrous histiocytoma (FH) has been histologically characterized as a "cellular" subtype. This variant is often mistaken for sarcoma, including dermatofibrosarcoma protuberans. We report a case of cellular FH of the skin in which the cytogenetic analysis demonstrated a novel chromosome pattern, possibly allowing distinction from its histologic simulants.

摘要

最近,一种独特的皮肤纤维组织细胞瘤(FH)变体在组织学上被特征化为“细胞性”亚型。这种变体常被误诊为肉瘤,包括隆突性皮肤纤维肉瘤。我们报告一例皮肤细胞性FH病例,其细胞遗传学分析显示出一种新的染色体模式,这可能有助于将其与组织学上相似的肿瘤区分开来。

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