Winn H R, Richardson A E, Jane J A
J Neurosurg. 1977 Nov;47(5):727-36. doi: 10.3171/jns.1977.47.5.0727.
The long-term evaluation of 60 patients who suffered a subarachnoid hemorrhage and survived 6 months is reported. By bilateral carotid arteriography, all patients were shown to have a single aneurysm at the vicinity of the posterior communicating artery at its junction with the internal carotid artery. The patients had previously been randomly assigned to treatment either by bed rest or by common carotid ligation. Average duration of survival among those followed is 8 years. Late rebleeding episodes were found to occur at a similar rate, irrespective of mode of treatment in the studied populations, but morbidity following operation continued to remain somewhat less over the ensuing years of follow-up study compared with the patients treated conservatively. On final assessment many years after the original hemorrhage, there is little improvement in degree of morbidity in either treatment group, and hypertension is noted to develop in the patients undergoing carotid ligation. A larger number of cases will be required to validate these findings.
报告了60例蛛网膜下腔出血且存活6个月患者的长期评估情况。通过双侧颈动脉血管造影,所有患者均显示在颈内动脉与后交通动脉交界处附近有单个动脉瘤。这些患者此前被随机分配接受卧床休息或颈总动脉结扎治疗。随访患者的平均存活时间为8年。发现迟发性再出血事件的发生率相似,在所研究人群中与治疗方式无关,但在随后的随访研究中,手术组的发病率在接下来的几年中仍比保守治疗的患者略低。在最初出血多年后的最终评估中,两个治疗组的发病程度几乎没有改善,且注意到接受颈动脉结扎的患者出现了高血压。需要更多病例来验证这些发现。