Almodovar J, Pérez S I, Arruza M, Morell C A, Báez A
Department of Otolaryngology, University of Puerto Rico School of Medicine, San Juan 00936-5067, USA.
P R Health Sci J. 1996 Dec;15(4):251-5.
This study comprised 134 patients who had developed head and neck squamous carcinoma (HNSCC), and attended the cancer clinics of the Otolaryngology Department at the Isaac González Martínez Oncologic Hospital between August 1993 and November 1995. In-person interviews, and medical record review of the HNSCC patients provided data on demography, family history of cancer, history of a second primary cancer, history of environmental, tobacco and ethanol exposure, and current disease status. The average age at the time of diagnosis was 62.3 (range 18-94), and eighty percent of the subjects were male. Most (59%) of the patients had moderately differentiated tumors and 14% had a recurrence of the carcinoma. The most frequent primary site in males was the laryngeal area, and the oral cavity in females. Exposure to alcohol and smoking were identified as predisposing factors in 95% of the patients.
本研究纳入了134例已发生头颈部鳞状细胞癌(HNSCC)的患者,这些患者于1993年8月至1995年11月期间在伊萨克·冈萨雷斯·马丁内斯肿瘤医院耳鼻喉科癌症门诊就诊。通过对HNSCC患者进行面对面访谈和病历审查,获得了有关人口统计学、癌症家族史、第二原发性癌症病史、环境、烟草和乙醇暴露史以及当前疾病状况的数据。诊断时的平均年龄为62.3岁(范围18 - 94岁),80%的受试者为男性。大多数(59%)患者患有中度分化肿瘤,14%的患者出现了癌症复发。男性最常见的原发部位是喉部,女性是口腔。95%的患者被确定酒精暴露和吸烟为诱发因素。