Yamakita N, Ikeda T, Murai T, Kimura M, Komaki T, Miura K, Iwamura M, Hirata T
Department of Internal Medicine, Matsunami General Hospital, Gifu.
Intern Med. 1997 Feb;36(2):107-12. doi: 10.2169/internalmedicine.36.107.
A 38-year-old male with panhypopituitarism due to Rathke's cleft cyst associated with a pituitary oncocytoma is reported. The presenting signs were general myalgia and slight fatigue. Endocrine examinations revealed panhypopituitarism. Magnetic resonance imaging disclosed a suprasellar cystic lesion of the pituitary gland. Cytological examination demonstrated ciliated cells in the mucinous fluid flowing from the cyst during the pituitary operation. A pituitary oncocytoma with randomly scattered S-100 immunoreactive cells was found upon histologic examination of the nodular tissue curettaged from the internal wall of the cyst. These results suggest that the pituitary adenoma was derived from folliculostellate cells included in the Rathke's cleft wall.
报告了一名38岁男性，因拉克氏裂囊肿合并垂体嗜酸性细胞瘤导致全垂体功能减退。主要症状为全身肌痛和轻度疲劳。内分泌检查显示全垂体功能减退。磁共振成像显示垂体鞍上囊性病变。垂体手术期间，细胞学检查显示囊肿流出的黏液中有纤毛细胞。对从囊肿内壁刮除的结节组织进行组织学检查时，发现了一个伴有随机散在的S-100免疫反应性细胞的垂体嗜酸性细胞瘤。这些结果表明，垂体腺瘤起源于拉克氏裂壁中的滤泡星状细胞。
