Benoist C, Mathis D
Institut de Génétique et de Biologie Moléculaire et Cellulaire (CNRS/INSERM/ULP), Strasbourg, France.
Curr Opin Immunol. 1997 Apr;9(2):245-9. doi: 10.1016/s0952-7915(97)80143-4.
Several studies reported during the past year, most of which exploited novel in vivo positive selection systems, have addressed the basis of peptide involvement in positive selection of T cells. The very flexible, yet specific, requirements the studies demonstrate differ somewhat from the very specific requirements reported in earlier experiments relying on in vitro selection systems.
在过去一年中报道的几项研究,其中大部分利用了新型的体内阳性选择系统,探讨了肽参与T细胞阳性选择的基础。这些研究所证明的非常灵活但又具有特异性的要求,与早期依赖体外选择系统的实验中所报道的非常具体的要求略有不同。