Kaneda Y, Nakayama H, Kagawa K, Furuta N, Ikuta T
Department of Neuropsychiatry, School of Medicine, University of Tokushima, Japan.
Tokushima J Exp Med. 1996 Dec;43(3-4):143-57.
Sex differences in flash visual evoked potentials (VEPs) and electroencephalograms (EEGs) were studied in 200 healthy adults (100 females and 100 males). Following results were obtained. (1) Waveforms of Group Mean VEPs of each sex had roughly triphasic contour, consisted of components P1 approximately N8, within 500 msec of latency. (2) Latencies of VEP components by t-test, (3) By analysis of covariance, sex differences in peak-to-peak amplitudes were still significant after eliminating effects of body height, body weight or age, but not those in latencies after eliminating the effect of body height. (4) Quantitative analysis of EEGs resulted in significantly smaller absolute amplitudes, and significantly larger theta, larger beta 1 and smaller alpha 2 power % in females. (5) Peak-to-peak amplitudes of later components in VEPs for 5CH (O1-->Cz) were significantly and positively correlated with EEG absolute amplitudes within each sex group. (6) There were few significant differences in VEP components between follicular phase and luteal phase in females. The sex differences in VEPs verified in this study may be attributed to genetically determined sex differences in neuroendocrinological systems.
对200名健康成年人（100名女性和100名男性）的闪光视觉诱发电位（VEP）和脑电图（EEG）的性别差异进行了研究。得到了以下结果。（1）各性别的组平均VEP波形大致呈三相轮廓，由潜伏期在500毫秒内的P1至N8成分组成。（2）通过t检验得出VEP成分的潜伏期，（3）通过协方差分析，在消除身高、体重或年龄的影响后，峰峰值振幅的性别差异仍然显著，但在消除身高影响后，潜伏期的性别差异不显著。（4）脑电图的定量分析结果显示，女性的绝对振幅明显较小，θ波、β1波明显较大，α2波功率百分比明显较小。（5）在每个性别组中，5CH（O1→Cz）的VEP后期成分的峰峰值振幅与脑电图绝对振幅呈显著正相关。（6）女性卵泡期和黄体期的VEP成分之间几乎没有显著差异。本研究中验证的VEP性别差异可能归因于神经内分泌系统中由基因决定的性别差异。
