Suzuki M, Ochi Y, Hosokawa S, Uemura N, Hosoi K, Kuniyoshi N, Inoue S, Matsuda M, Kishi S, Matsuoka R
Department of Internal Medicine, National Kochi Hospital, Japan.
Tokushima J Exp Med. 1996 Dec;43(3-4):173-6.
The patient was a 31 year old male complaining discomfort in the epigastrium. Endoscopy of the upper gastrointestinal tract indicated multiple gastric ulcers. Biopsy specimen taken from the ulcerous region indicated giant cells accompanying intranuclear inclusion bodies in the gastric mucosa. Since the patient tested positive to cytomegalovirus (CMV)-IgM antibody, he was assumed to have gastric ulcers caused by CMV infection. However, the patient was cured without the administration of antiviral agent because no definite immunodeficiency status was observed. The result of present study indicated that endoscopic biopsy is useful for diagnosing gastrointestinal lesion attributable to CMW infection.
该患者为一名31岁男性,主诉上腹部不适。上消化道内镜检查显示多处胃溃疡。从溃疡部位采集的活检标本显示胃黏膜中有伴有核内包涵体的巨细胞。由于该患者巨细胞病毒(CMV)-IgM抗体检测呈阳性,推测其胃溃疡由CMV感染引起。然而,由于未观察到明确的免疫缺陷状态,该患者未使用抗病毒药物就治愈了。本研究结果表明,内镜活检有助于诊断由CMW感染引起的胃肠道病变。