Domínguez F, Riera J R, Tojo S, Junco P
Department of Pathology, "Valle del Nalón" Hospital (Instituto Nacional de la Salud), Langreo, Asturias, Spain.
Acta Cytol. 1997 Mar-Apr;41(2):341-7. doi: 10.1159/000332522.
To determine the diagnostic efficacy of breast fine needle aspiration (FNA) in the routine practice of a community hospital.
The study group consisted of 1,398 consecutive FNA biopsies of the female breast performed at our institution during a five-year period; 450 (32%) had histologic follow-up. Both FNA and the histologic diagnosis were compared in order to establish the accuracy, efficiency and safety of the FNA breast technique.
The sensitivity of the FNA procedure was 93.49% and specificity 95.73%, with a predictive value for a positive diagnosis of 93.49% and for a negative diagnosis, 95.73%. The overall diagnostic accuracy was 94.84%, and the sensitivity of cytologic diagnosis was 98.75%. The false negative and false positive rates were 2.5%, including 10 cases with suspicious diagnoses and only 1 false positive diagnosis (0.23%). The false positive and false negative cases were recorded as having no effect or a minimal effect on patient management, and no mastectomy was performed because of this FNA diagnosis.
FNA breast biopsy is an efficient tool for diagnosis when performed by surgical pathologists with cytologic training but not exclusively dedicated to cytopathology.
