Mallow D W, Humphrey P A, Soper J T, Johnston W W
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Acta Cytol. 1997 Mar-Apr;41(2):549-55. doi: 10.1159/000332555.
Malignant tumors with extragenital origins are rare in cervicovaginal samples.
A case of metastatic lobular carcinoma of the breast was diagnosed in a cervicovaginal smear. Histologic correlation was performed. Marker studies for carcinoembryonic antigen, human milk fat globule membrane, epidermal growth factor receptor, epithelial membrane antigen and cytokeratin were positive.
Recognition of extrauterine cancer in the cervicovaginal smear has important diagnostic, prognostic, and therapeutic implications.
宫颈阴道样本中起源于生殖器外的恶性肿瘤罕见。
在宫颈阴道涂片检查中诊断出一例乳腺小叶癌转移病例。进行了组织学相关性分析。癌胚抗原、人乳脂肪球膜、表皮生长因子受体、上皮膜抗原和细胞角蛋白的标记物研究均呈阳性。
在宫颈阴道涂片中识别宫外癌症具有重要的诊断、预后和治疗意义。
