Kendall B S, Liang C Y, Lancaster K J, McCabe K M, Solanki P H
Department of Pathology, Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236-5300, USA.
Acta Cytol. 1997 Mar-Apr;41(2):598-602. doi: 10.1159/000332565.
Ischemic fasciitis, also called atypical decubital fibroplasia, was recently described as a distinctive fibroblastic proliferation occurring predominantly in elderly, bed-ridden individuals. This entity can easily be misdiagnosed as a malignant process.
A 70-year-old, white male presented with an enlarging right hip mass. Fine needle aspiration yielded spindled and ovoid cells with ample cytoplasm and occasional nuclear atypia. The histologic features of a subsequent biopsy and resection specimen included a zonal pattern of fibrinoid necrosis with surrounding reactive fibroblasts, histiocytes and vascular proliferation, which are characteristic of ischemic fasciitis.
Ischemic fasciitis can be mistaken clinically, cytologically and histologically for sarcoma. The cytologic findings seen in this case, when combined with the clinical history, were sufficient to avoid misdiagnosis of malignancy in a benign, proliferative lesion.
缺血性筋膜炎,也称为非典型褥疮性纤维增生,最近被描述为一种主要发生在老年卧床患者中的独特的成纤维细胞增生。该病变很容易被误诊为恶性病变。
一名70岁的白人男性,右髋部肿物逐渐增大。细针穿刺抽吸获得梭形和卵圆形细胞,胞质丰富,偶尔有核异型性。后续活检和切除标本的组织学特征包括纤维蛋白样坏死的带状模式,周围有反应性成纤维细胞、组织细胞和血管增生,这些都是缺血性筋膜炎的特征。
缺血性筋膜炎在临床、细胞学和组织学上都可能被误诊为肉瘤。结合该病例的临床病史,其细胞学表现足以避免将良性增生性病变误诊为恶性病变。