一种评估平均冠状动脉血流的新密度测定方法。
A new densitometric approach to the assessment of mean coronary flow.
作者信息
Dorsaz P A, Doriot P A, Dorsaz L, Chatelain P, Rutishauser W
机构信息
Cardiology Center, University Hospital of Geneva, Switzerland.
出版信息
Invest Radiol. 1997 Apr;32(4):198-204. doi: 10.1097/00004424-199704000-00002.
RATIONALE AND OBJECTIVES
The authors present an angiographic method to measure absolute coronary blood flow in patients.
METHODS
The left or right coronary tree is three-dimensional (3D)-reconstructed from biplane coronary angiograms. This allows the determination of the intravascular volumes needed for flow measurement. The 3D distance traveled by the contrast medium during one cardiac cycle is determined by appropriately thresholding the "concentration-distance", curves computed on two pairs of images taken one cardiac cycle apart.
RESULTS
The angiographic flow measurements were compared with nearly simultaneous flow determinations obtained with an intracoronary ultrasonic Doppler flow velocity measuring device. The mean relative difference between the Doppler and the 3D measurements was 11% and the two sets of flow values correlated well (r = 0.81).
CONCLUSIONS
A method for the determination of mean coronary flow is presented. The procedure is simple and can be incorporated easily into clinical routine.
原理与目的
作者介绍了一种测量患者冠状动脉绝对血流量的血管造影方法。
方法
利用双平面冠状动脉造影对左或右冠状动脉树进行三维（3D）重建。这使得能够确定流量测量所需的血管内体积。通过对在一个心动周期内相隔拍摄的两对图像上计算得到的“浓度-距离”曲线进行适当阈值处理，来确定造影剂在一个心动周期内行进的3D距离。
结果
将血管造影流量测量结果与使用冠状动脉内超声多普勒流速测量装置几乎同时获得的流量测定结果进行比较。多普勒测量值与3D测量值之间的平均相对差异为11%，两组流量值具有良好的相关性（r = 0.81）。
结论
提出了一种测定平均冠状动脉血流量的方法。该程序简单，可轻松纳入临床常规操作。
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