Ceriatti F S, Rovera M, Sabini L I, Godino S D
Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas Fisico-Química y Naturales, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
Enferm Infecc Microbiol Clin. 1997 Feb;15(2):88-90.
Most mucose-cutaneous infections can be diagnosed by clinical history with explorative technique. Nevertheless the definitive etiologic diagnostic can only be established with the help of the isolation and identification of the causal agent.
We reported a case of generalized infection in a new born, with is clinical characteristics, virological diagnostic techniques and treatment of the disease.
Herpes simplex virus was isolated in Vero cellular culture from CRL and vesiculose lesions of the child's thorax region and from the mothers endocervical scrapes. The agent was identified by seroneutralization test. This confirmed a perinatal transmission of Herpes simplex virus type 2. The tomographic studies revealed characteristic alterations of a viral encephalitis. An antiviral treatment was useful in this therapy.
Our results demonstrate the importance of an early viral diagnostic which permits the applications of specific treatment and thus the prevention of severe complications.
大多数黏膜皮肤感染可通过临床病史及探查技术进行诊断。然而，只有通过分离和鉴定病原体才能确立明确的病因诊断。
我们报告了一例新生儿全身性感染病例，包括其临床特征、病毒学诊断技术及疾病治疗情况。
在Vero细胞培养中，从患儿胸部区域的结痂和水疱性皮损以及母亲的宫颈刮片中分离出单纯疱疹病毒。通过血清中和试验鉴定该病原体。这证实了2型单纯疱疹病毒的围产期传播。断层扫描研究显示了病毒性脑炎的特征性改变。抗病毒治疗在该治疗中有效。
我们的结果表明早期病毒诊断的重要性，其有助于应用特异性治疗从而预防严重并发症。
