Riesener K P, Höfer M, Virnich N, Füzesi L, Schumpelick V
Chirurgische Universitätsklinik und Poliklinik, RWTH Aachen.
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:1040-2.
Between 1885 and 1991 only 71 cases of malignant pancreatic tumours in childhood and adolescence have been reported in literature; the majority of these were pancreatoblastomas. The symptoms, pathology and therapy of this rare tumour are demonstrated in the case of a 17-year-old girl. The tumour is believed to develop at an early stage of pancreatic cell differentiation. Usually it is composed of both exocrine and endocrine cell types. The treatment of choice is radical resection. In contrast to pancreatic neoplasms in adult patients the pancreatoblastoma has a favourable prognosis. The role of adjuvant chemotherapy or radiotherapy is still under discussion due to the small number of patients treated as yet.
1885年至1991年间，文献中仅报道了71例儿童和青少年期的恶性胰腺肿瘤；其中大多数为胰腺母细胞瘤。本文通过一名17岁女孩的病例展示了这种罕见肿瘤的症状、病理及治疗方法。该肿瘤被认为是在胰腺细胞分化的早期阶段发生的。通常它由外分泌和内分泌细胞类型组成。首选的治疗方法是根治性切除术。与成年患者的胰腺肿瘤不同，胰腺母细胞瘤的预后良好。由于目前接受治疗的患者数量较少，辅助化疗或放疗的作用仍在讨论中。
