Schmidt B, Höllwarth M E, Schalamon J, Urban C
Universitätsklinik für Kinderchirurgie, Graz.
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:1070-2.
Between 1984 and 1994 operations for thoracic neuroblastomas were performed in ten patients (six boys, four girls). The median age was 17 months, the follow-up ranges between 6 months and 11 years; one patient died 3 years postoperatively. Complete excision of the tumour was the only therapy in four patients presenting with stage I (n = 2) and II a (n = 2) disease. Following resection, chemotherapy was carried out in four patients with stage II b (n = 2) and III (n = 2). Chemotherapy was the primary procedure in two patients with stage IV; resection of the tumour and postoperative chemotherapy followed. Thoracic neuroblastomas have a favorable outcome. The basic biology seems to differ from that of other sites and may not warrant such aggressive surgical therapy. Complete excision is recommended, if possible, but is not imperative.
1984年至1994年间,对10例胸段神经母细胞瘤患者(6例男孩,4例女孩)进行了手术。中位年龄为17个月,随访时间为6个月至11年;1例患者术后3年死亡。对于4例I期(n = 2)和II a期(n = 2)疾病的患者,肿瘤完全切除是唯一的治疗方法。切除术后,对4例II b期(n = 2)和III期(n = 2)的患者进行了化疗。化疗是2例IV期患者的主要治疗方法;随后进行肿瘤切除和术后化疗。胸段神经母细胞瘤预后良好。其基本生物学特性似乎与其他部位不同,可能不需要如此积极的手术治疗。如果可能,建议完全切除,但并非必须。