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[年龄、性别、遗传及外源性因素作为药物血浆蛋白结合的决定因素]

[Age, sex, genetic and exogenous factors as determinants of plasma protein binding of drugs].

作者信息

Lutsevich A N

出版信息

Vestn Ross Akad Med Nauk. 1996(12):26-31.

PMID:9102076
Abstract

The data on relations of individual variations in the plasma protein binding of drugs to age, sex, genetic monitoring, and some environmental factors among which food and lifestyle (smoking, alcohol and coffee consumption, exercise, etc.) are of much importance. Individual variability in the plasma protein binding of drugs may be of great significance for pharmacokinetics and pharmacodynamics.

摘要

关于药物血浆蛋白结合的个体差异与年龄、性别、基因监测以及一些环境因素(其中食物和生活方式,如吸烟、饮酒、喝咖啡及运动等)之间关系的数据。药物血浆蛋白结合的个体差异对于药代动力学和药效学可能具有重要意义。

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