Liubchanskiĭ E R, Sokhranich A L, Sokol'nikov M E
Radiats Biol Radioecol. 1997 Jan-Feb;37(1):105-10.
The behavior of plutonium in the organism and the mechanism of formation of absorbed doses in rats of different age were studied in a comparative aspect. The efficiency of CaDTPA depending on the animal's age and the usage was estimated. Under similar conditions, the efficiency of early single injections of CaDTPA to rat cubs was 2.3 (skeleton) or 3.3 (liver) times lower than that for mature rats. Attempts of modifying the kinetics of low-transportable plutonium-239 by stimulation of pulmonary alveolar macrophages failed.
从比较的角度研究了钚在生物体内的行为以及不同年龄大鼠吸收剂量的形成机制。评估了依地酸钙钠(CaDTPA)的有效性,该有效性取决于动物年龄和使用情况。在相似条件下,对幼鼠早期单次注射依地酸钙钠的有效性比成年大鼠低2.3倍(骨骼)或3.3倍(肝脏)。通过刺激肺泡巨噬细胞来改变低迁移性钚-239动力学的尝试未成功。