Rühlmann C, Walther T, Walter T, Wittig K, Reschke I
Medizinische Klinik und Poliklinik I, Universität Leipzig.
Dtsch Med Wochenschr. 1997 Mar 7;122(10):287-92. doi: 10.1055/s-2008-1047610.
On the day before admission a 68-year-old woman had an acute episode of incomplete ischaemia of the left lower arm. She had no known heart disease and her general condition was unchanged. There were no palpable pulses in the cold and pale lower arm. Sensory and motor functions of the left hand were slightly impaired. Arterial embolisation was suspected.
The blood picture was normal, erythrocyte sedimentation rate 20/50 mm, C-reactive protein elevated to 7.0 mg/l. There was no evidence of clotting abnormality. The resting ECG showed normal sinus rhythm. Doppler ultrasound gave a systolic pressure of 80 mm Hg over the radial artery and 50 mm Hg over the ulnar artery, with a systemic systolic pressure of 140 mm Hg. No intracardiac thrombi were seen on echocardiography. Transoesophageal echocardiography revealed a 2 x 3 cm hypermobile mass in the distal aortic arch, most likely a thrombus as the source of the embolus. Contrast computed tomography and digital subtraction angiography also demonstrated the mass.
At first heparin (bolus of 5000 IU, then 1000 IU/h) was infused. One day after the diagnosis had been established thrombectomy of the aortic arch and embolectomy of the left brachial artery were performed without complication. The patient was discharged on the 15th post-operative day on a maintenance dose of phenprocoumon. Histological examination of the surgical specimen from the aorta showed a separating thrombus on an ulcerating atherosclerotic plaque.
The importance of the thoracic aorta as a source of emboli is often underestimated. Transoesophageal echocardiography is a reliable method to demonstrate aortic thrombi.
入院前一天,一名68岁女性出现左前臂急性不完全缺血发作。她无已知心脏病史,一般状况未变。冰冷、苍白的前臂未触及脉搏。左手感觉和运动功能稍有受损。怀疑为动脉栓塞。
血常规正常,红细胞沉降率20/50mm,C反应蛋白升高至7.0mg/l。无凝血异常证据。静息心电图显示正常窦性心律。多普勒超声显示桡动脉收缩压为80mmHg,尺动脉收缩压为50mmHg,全身收缩压为140mmHg。超声心动图未发现心内血栓。经食管超声心动图显示主动脉弓远端有一个2×3cm的活动度高的团块,很可能是血栓,为栓子来源。对比计算机断层扫描和数字减影血管造影也显示了该团块。
起初输注肝素( bolus 5000IU,然后1000IU/h)。确诊一天后,行主动脉弓血栓切除术和左肱动脉栓子切除术,无并发症。患者术后第15天出院,服用维持剂量的苯丙香豆素。主动脉手术标本的组织学检查显示,在溃疡性动脉粥样硬化斑块上有一个分离的血栓。
胸主动脉作为栓子来源的重要性常被低估。经食管超声心动图是显示主动脉血栓的可靠方法。