Radovanović Lj
Institute for Kidney Diseases and Metabolic Disorders, Zvezdara Clinical and Hospital Centre, Belgrade.
Srp Arh Celok Lek. 1996;124 Suppl 1:151-3.
One dose vancomycinum was successful in treatment of peritonitis in patients undergoing chronic peritoneal dialysis if it was used after initial signs of disease immediately. Thirteen episodes of peritonitis treated in that manner were analysed. Microorganisms isolated previously were: Staphylococcus epidermidis in seven. Enterococcus in three, while no organisms were isolated in three cases. Vancomycinum was applied at the same time intravenously 0.5 g and intraperitoneally 0.5 g in the peritoneal solution for the six to eighteen hours. The treatment was successful in ten and failed in three cases with other medical complications: the tunnel infection in two and Tenckhoff catheter obstruction in one patient. The advantage of such treatment is in healing of most patients, it is cheap, the small drug dose diminishes its toxic effects and the duration of the hospital care is only one day. Anyway, it is not recommended in the treatment of patients with catheter obstruction, tunnel infection and other complications.
