Kruscić D, Pejcić I, Kostić M, Jovanović O, Peco-Antić A, Popović-Rolović M
University Children's Hospital, Belgrade.
Srp Arh Celok Lek. 1996;124 Suppl 1:90-1.
Vesicoureteral reflux and reflux nephropathy are causes of end-stage renal failure in 43 percent of our patients on haemodialysis. Aiming at early discovering of vesicoureteral reflux and preventing reflux nephropathy, we started an investigation of the familial character or the primary vesicoureteral reflux in the families of 44 our patients with the diagnosed anomaly. Investigations which consist of urinalysis, urine culture and ultrasound of kidneys have so far been carried out for siblings of our patients in ten families. Complete investigations, including voiding cystourethrogram where indicated, have been carried out in five families. Familial vesicoureteral reflux ascertained in three families.
膀胱输尿管反流和反流性肾病是我们43%接受血液透析的患者终末期肾衰竭的病因。为了早期发现膀胱输尿管反流并预防反流性肾病，我们对44例已确诊该异常的患者家庭中的原发性膀胱输尿管反流的家族特征展开了调查。到目前为止，我们已对10个家庭中患者的兄弟姐妹进行了包括尿液分析、尿培养和肾脏超声检查在内的调查。在5个家庭中进行了全面检查，包括必要时的排尿性膀胱尿道造影。在3个家庭中确定存在家族性膀胱输尿管反流。
