Beleva S, Enikova R, Vachkov P
National Center of Hygiene, University Infectious Hospital, Sofia, Bulgaria.
Zh Mikrobiol Epidemiol Immunobiol. 1996 Nov-Dec(6):16-20.
A case of an acute disease with a rapid clinical course and a fatal outcome in the presence of irreversible toxicoinfectious shock, appearing in two children after the consumption of sheep kidneys, is described. The post mortem examination of the children revealed the presence of hemorrhagic, erosive and necrotic areas on the mucous membrane of the stomach, the duodenum and the upper section of the small intestine. From the material obtained by probing the stomach of one of the children 6 hours before death P.asaccharolyticus and B.cereus were isolated. Hemorrhage, erosions and necrosis were also found in experimental mice, injected with the centrifugates of the gastric secretions of the patient and the cultures of the isolated bacteria, which was indicative of the presence of highly active exotoxin. On the basis of the above facts, compared with similar data in the literature, this case was considered to be etiologically related anaerobic Peptostreptococcus in symbiosis with B.cereus.
本文描述了一例急性疾病，临床病程迅速，在不可逆的中毒性感染性休克情况下导致死亡，该疾病出现在两名食用羊肾后的儿童身上。对儿童进行的尸检显示，胃、十二指肠和小肠上段的黏膜存在出血、糜烂和坏死区域。在其中一名儿童死亡前6小时从其胃内容物中分离出解糖胨普雷沃菌和蜡样芽孢杆菌。在注射了患者胃分泌物离心物和分离细菌培养物的实验小鼠中也发现了出血、糜烂和坏死，这表明存在高活性外毒素。基于上述事实，并与文献中的类似数据进行比较，该病例被认为在病因上与与蜡样芽孢杆菌共生的厌氧消化链球菌有关。
