Cady B
Harvard Medical School, Boston, Massachusetts, USA.
Surg Oncol Clin N Am. 1997 Apr;6(2):195-202.
Mammographic screening produces markedly smaller breast cancers with fewer axillary lymph nodes and more ductal carcinoma in situ. Over the past 25 years at the New England Deaconess Hospital, the mean maximum diameter of breast cancers has decreased by 10% every 5 years and is now only 2.1 cm. The median maximum diameter in the years from 1989 to 1993 is only 1.5 cm. Axillary lymph node metastases also are declining progressively. This continuing decline in mean and median maximum diameters and incidence of axillary lymph node metastases shows no signs of abating at the present time. Universal mammographic screening of appropriately aged women should be a public health goal to further this trend towards markedly earlier breast cancer detection with much higher survival and new opportunities for modified therapy.
乳房X光筛查检出的乳腺癌明显更小，腋窝淋巴结转移更少，原位导管癌更多。在过去25年里，新英格兰女执事医院的乳腺癌平均最大直径每5年下降10%，目前仅为2.1厘米。1989年至1993年期间的最大直径中位数仅为1.5厘米。腋窝淋巴结转移也在逐渐减少。平均和最大直径中位数以及腋窝淋巴结转移发生率的持续下降目前没有减弱的迹象。对适龄女性进行普遍的乳房X光筛查应成为一项公共卫生目标，以推动这一朝着更早发现乳腺癌、更高生存率以及改良治疗新机会发展的趋势。
