Rohde T D, Blackshear P J, Varco R L, Buchwald H
Trans Am Soc Artif Intern Organs. 1977;23:13-6. doi: 10.1097/00002480-197700230-00004.
This study demonstrates the feasibility of ambulatory heparin therapy and its potential for successful treatment of refractory thromboembolic disease. The proven capability of the implantable infusion pump to provide long-term heparin infusion in ambulatory subjects suggests that it may have application in the delivery of other parenteral drugs as well.
本研究证明了门诊肝素治疗的可行性及其成功治疗难治性血栓栓塞性疾病的潜力。可植入输液泵在门诊患者中提供长期肝素输注的已证实能力表明,它也可能在其他胃肠外药物的给药中得到应用。