Imaizumi T
Landmark Clinic, Yokohama, Japan.
Kekkaku. 1997 Mar;72(3):147-51.
It has been observed that lung tuberculosis shows a similar pathological feature with that of sarcoidosis. Serum angiotensin converting enzyme (ACE) was elevated in sarcoidosis. In the present study, serum ACE was measured in pulmonary tuberculosis patients. 1. ACE showed lower level in active tuberculosis. Elevation of serum ACE, however, was observed during the treatment. 2. Serum ACE was low in cases with chronic fibrotic pulmonary tuberculosis with extensive shadows on chest X-P. 3. Improvement of infiltrative shadows on chest X-P paralleled with the elevation of serum ACE. It was suggested that the new development of lung capillary endothelium might cause the elevation of ACE during the improving process of active pulmonary tuberculosis.
据观察，肺结核与结节病表现出相似的病理特征。结节病患者血清血管紧张素转换酶（ACE）升高。在本研究中，对肺结核患者的血清ACE进行了检测。1. 活动性肺结核患者的ACE水平较低。然而，在治疗期间观察到血清ACE升高。2. 慢性纤维空洞型肺结核且胸部X线有广泛阴影的患者血清ACE水平较低。3. 胸部X线浸润阴影的改善与血清ACE升高平行。提示在活动性肺结核病情改善过程中，肺毛细血管内皮的新生可能导致ACE升高。
