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以截瘫为表现的胸膜B细胞淋巴瘤

[Pleural B cell lymphoma presenting as paraplegia].

作者信息

Hashizume T, Honda A, Shimada H, Eto T, Akiyama J, Yamakawa H, Ikehara K, Ito M, Fujii M, Arai K

机构信息

Department of Respiratory Medicine, Shizuoka General Hospital, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Feb;35(2):205-9.

PMID:9103860
Abstract

A 54-year-old man felt pain on the right side of his chest. Two months later, paraplegia developed. A chest CT scan revealed a pleural effusion and a mass lesion along the right parietal pleura. The lesion extended directly into the adjacent part of the spinal canal and compressed the spinal cord. Cytologic examination of the pleural effusion revealed atypical lymphoid cells, and examination of a transcutaneous biopsy specimen showed monotonous atypical B lymphocytes. The diagnosis was pleural malignant lymphoma. Chemotherapy induced a partial remission, but 14 months after the first examination he died of central nervous system involvement. Pleural lymphoma can directly compress the spinal cord and cause paraplegia. Early diagnosis and therapy greatly affect the outcome in patients with spinal cord compression.

摘要

一名54岁男性感到右侧胸部疼痛。两个月后,出现了截瘫。胸部CT扫描显示有胸腔积液以及沿右壁层胸膜的肿块病变。该病变直接延伸至椎管的相邻部位并压迫脊髓。胸腔积液的细胞学检查发现非典型淋巴细胞,经皮活检标本检查显示为单一形态的非典型B淋巴细胞。诊断为胸膜恶性淋巴瘤。化疗诱导了部分缓解,但在首次检查14个月后,他死于中枢神经系统受累。胸膜淋巴瘤可直接压迫脊髓并导致截瘫。早期诊断和治疗对脊髓受压患者的预后有很大影响。

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