Nakamura S, Nakayama T
Third Department of Internal Medicine, Hiroshima University School of Medicine.
Nihon Rinsho. 1997 Apr;55(4):833-8.
The rapid diagnosis of viral infection in nervous system is necessary for the effective treatment, since they progress so rapidly. The identification of infected virus can be achieved by amplifying DNA or RNA in virus, using polymerase chain reaction (PCR). Herpes simplex encephalitis is the most common and fruitful target for genetic diagnosis. Genetic diagnosis can also detect the presence of cytomegalovirus, EB virus, human herpes 6 virus, herpes zoster virus, HTLV-1 (human T-lymphotrophic virus type 1), measles virus, mumps virus, Japanese encephalitis virus, rubella virus, HIV (human immunodeficiency virus), and HCV (hepatitis C virus). However, the presence of the virus does not always mean a recent infection by the virus, nor a cause of the disease.
由于病毒感染进展迅速,因此对神经系统病毒感染进行快速诊断对于有效治疗至关重要。通过聚合酶链反应(PCR)扩增病毒中的DNA或RNA,可实现对感染病毒的鉴定。单纯疱疹性脑炎是基因诊断最常见且最有成效的目标。基因诊断还可检测巨细胞病毒、EB病毒、人类疱疹病毒6型、带状疱疹病毒、人类嗜T淋巴细胞病毒1型(HTLV-1)、麻疹病毒、腮腺炎病毒、日本脑炎病毒、风疹病毒、人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)的存在。然而,病毒的存在并不总是意味着近期感染了该病毒,也不一定是疾病的病因。