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Genetic heterogeneity of familial atrial myxoma syndromes (Carney complex).

作者信息

Basson C T, MacRae C A, Korf B, Merliss A

机构信息

Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

出版信息

Am J Cardiol. 1997 Apr 1;79(7):994-5. doi: 10.1016/s0002-9149(97)00033-7.

DOI:10.1016/s0002-9149(97)00033-7
PMID:9104925
Abstract

Familial atrial myxomas may present as a component of the Carney complex, an autosomal dominant multiple neoplasia and lentiginosis syndrome. Although a gene defect for the Carney complex in some families maps to chromosome 2p, this syndrome is genetically heterogeneous, and other genetic loci also produce familial atrial myxomas.

摘要

相似文献

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Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.卡尼综合征,一种家族性多发性肿瘤和雀斑综合征。对11个家系的分析及与2号染色体短臂的连锁关系。
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Carney complex.卡尼综合征
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Evidence for a second genetic locus in Carney complex.卡尼综合征中第二个基因位点的证据。
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