Lawrence J D, Lawrence D B, Carson D S
Medical Universityof South Carolina College of Medicine, Charleston, USA.
Am Fam Physician. 1997 Apr;55(5):1705-9, 1711-2.
Rapid-release psychostimulants are commonly used to treat attention-deficit hyperactivity disorder (ADHD), but midday dosing requirements and poor compliance rates have prompted the development of sustained-release formulations. Sustained-release methylphenidate has been shown to have efficacy equal to that of the regular-release formulation and may be preferable when it is difficult or impossible to provide midday doses. Proper management of ADHD includes choosing the proper medication dosage, minimizing side effects of medications and periodically reevaluating the patient's progress.
速释型精神振奋药物常用于治疗注意力缺陷多动障碍（ADHD），但午间给药需求以及较差的依从率促使了缓释制剂的研发。已证明缓释型哌甲酯的疗效与速释型制剂相当，并且在难以或无法提供午间剂量时可能更具优势。ADHD的妥善管理包括选择合适的药物剂量、将药物副作用降至最低以及定期重新评估患者的进展情况。
