Mastroianni A, Coronado O, Scarani P, Manfredi R, Chiodo F
Dipartimento di Medicina Clinica Specialistica, Policlinico San Orsola, Università degli Studi, Bologna.
Minerva Med. 1997 Mar;88(3):101-4.
In recent years, Toxoplasma gondii has emerged as an important life-threatening opportunistic pathogen in compromised hosts. Toxoplasma gondii is considered the opportunistic agent most frequently causing severe encephalitis in AIDS. Less common manifestations of active toxoplasma infection include extracerebral and disseminated disease. The diagnosis of extraneural or disseminated toxoplasmosis requires a high index of suspicion because the clinical and laboratory manifestations are nonspecific and may be confused with those of other opportunistic diseases. The authors report an unusual case of anergic disseminated toxoplasmosis in AIDS, with a brief comment on the clinical and diagnostic aspects of this rare, dangerous, but treatable complication.
近年来，弓形虫已成为免疫功能低下宿主中一种重要的、危及生命的机会性病原体。弓形虫被认为是艾滋病患者中最常导致严重脑炎的机会性病原体。活动性弓形虫感染较少见的表现包括脑外和播散性疾病。神经外或播散性弓形虫病的诊断需要高度怀疑，因为其临床和实验室表现不具特异性，可能与其他机会性疾病的表现相混淆。作者报告了1例艾滋病患者发生的无反应性播散性弓形虫病的罕见病例，并对这种罕见、危险但可治疗的并发症的临床和诊断方面作简要评论。
