Toshiaki Y, Yoshio O, Kayo S, Eriko K, Takayuki K
Department of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan.
Acta Otolaryngol. 1997 Mar;117(2):135-8. doi: 10.3109/00016489709117754.
Three-dimensional analysis of nystagmus was carried out in patients with peripheral vestibular diseases using a computerized image recognition technique developed by us. In the present study, we analyzed data from patients with Meniere's disease and vestibular neuritis with the central premise of localizing the pathology in the peripheral vestibular organs. In Meniere's disease, the recordings of all subjects showed two components of eye movements, namely the horizontal and torsional components. On the other hand, most of the patients with vestibular neuritis exhibited all three components of spontaneous nystagmus. The horizontal and vertical components of nystagmus in patients with vestibular neuritis were directed towards the contralateral side of the lesion and upwards. Based on these results and with reference to animal experiments that have related the eye movements with each labyrinthine end organ, it can be speculated that in Meniere's disease the pathological changes may involve all semicircular canals, whereas the main site of lesion in vestibular neuritis could be localized to the superior vestibular nerve.
我们使用自行开发的计算机图像识别技术，对周围性前庭疾病患者进行了眼球震颤的三维分析。在本研究中，我们以将病变定位于周围前庭器官为核心前提，分析了梅尼埃病和前庭神经炎患者的数据。在梅尼埃病中，所有受试者的记录均显示出两种眼球运动成分，即水平成分和扭转成分。另一方面，大多数前庭神经炎患者表现出自发性眼球震颤的所有三种成分。前庭神经炎患者眼球震颤的水平和垂直成分指向病变的对侧并向上。基于这些结果，并参考将眼球运动与每个迷路终末器官相关联的动物实验，可以推测，在梅尼埃病中，病理变化可能涉及所有半规管，而前庭神经炎的主要病变部位可能定位于上前庭神经。
