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猫听觉脑干反应的起源:全脑干图谱以及下丘的损伤和辣根过氧化物酶研究

Origin of auditory brainstem responses in cats: whole brainstem mapping, and a lesion and HRP study of the inferior colliculus.

作者信息

Kaga K, Shinoda Y, Suzuki J I

机构信息

Department of Otolaryngology, University of Tokyo, Japan.

出版信息

Acta Otolaryngol. 1997 Mar;117(2):197-201. doi: 10.3109/00016489709117768.

DOI:10.3109/00016489709117768
PMID:9105447
Abstract

In order to identify the origin of five waves of auditory brainstem responses (ABRs) in cats, we designed three experiments. In particular, we focused on the inferior colliculus (IC). Experiment 1: Evoked potential maps of the frontal sections of the brainstem from the level of the cochlear nuclei to the level of the ICs were constructed from the results of whole brainstem field-potential analysis comparing ABR peaks. Experiment 2: Both ICs were aspirated and the brainstem and midbrian were transected along the midline. Experiment 3: HRP was injected to the central nucleus of the IC to cause phase reversal of field potentials, and localization of brainstem auditory neurons projecting to the IC was studied. The results of these experiments suggest that each wave of the ABR is elicited from multiple sources of auditory brainstem nuclei and tracts only.

摘要

为了确定猫听觉脑干反应(ABR)五波的起源,我们设计了三个实验。特别地,我们聚焦于下丘(IC)。实验1:通过比较ABR波峰的全脑干场电位分析结果,构建从耳蜗核水平到下丘水平的脑干额状切面诱发电位图。实验2:双侧下丘被吸出,脑干和中脑沿中线横断。实验3:将辣根过氧化物酶(HRP)注入下丘中央核以引起场电位的相位反转,并研究投射到下丘的脑干听觉神经元的定位。这些实验结果表明,ABR的每一波仅由听觉脑干核团和神经束的多个来源引出。

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