鲤鱼和虹鳟鱼细胞色素c氧化酶亚基VIa的cDNA序列表明鱼类中不存在同工型。
The cDNA sequences of cytochrome c oxidase subunit VIa from carp and rainbow trout suggest the absence of isoforms in fishes.
作者信息
Hüttemann M, Exner S, Arnold S, Lottspeich F, Kadenbach B
机构信息
Fachbereich Chemie, Philipps-Universität, Marburg, Germany.
出版信息
Biochim Biophys Acta. 1997 Mar 28;1319(1):14-8. doi: 10.1016/s0005-2728(97)00011-x.
The cDNAs of subunit VIa of cytochrome c oxidase from rainbow trout liver and carp heart are presented, revealing 82% identity of their deduced amino acid sequences. The two cDNAs are evolutionary equally distant from the livertype (VIaL) and heart-type (VIaH) of mammalian subunit VIa. The data suggest that in ectotherm fishes no isoforms of subunit VIa occur, and that the postulated tissue-specific mechanism of thermogenesis in mammals, based on interaction of ATP with subunit VIaH (Frank, V. and Kadenbach, B. (1996) FEBS Lett. 382, 121-124), is absent.
本文展示了虹鳟鱼肝和鲤鱼心脏中细胞色素c氧化酶亚基VIa的cDNA，其推导的氨基酸序列显示出82%的同一性。这两个cDNA在进化上与哺乳动物亚基VIa的肝型（VIaL）和心脏型（VIaH）距离相等。数据表明，在变温鱼类中不存在亚基VIa的同工型，并且基于ATP与亚基VIaH相互作用的哺乳动物中假定的组织特异性产热机制（Frank, V.和Kadenbach, B. (1996) FEBS Lett. 382, 121 - 124）并不存在。
Zotero 插件