模拟视神经炎的视神经转移瘤。

Optic nerve metastasis simulating optic neuritis.

作者信息

Pengel J, Crevits L, Wynants P, De Poorter M C, Mastenbroek G G, De Reuck J

机构信息

Department of Neurology, University Hospital of Ghent, Belgium.

出版信息

Clin Neurol Neurosurg. 1997 Feb;99(1):46-9. doi: 10.1016/s0303-8467(96)00559-8.

DOI:10.1016/s0303-8467(96)00559-8

PMID:9107468

Abstract

A 68-year-old man developed subacutely bilateral loss of visual acuity without any other neurological sign. Magnetic resonance images showed some small scattered periventricular white matter T2 hypersignals. On spinal fluid analysis a mononuclear pleocytosis and an oligoclonal gamma-pattern was found. Treatment with intravenous corticosteroids had no effect. The clinical situation deteriorated and the patient died of bronchopneumonia. Postmortem examination revealed manifest metastatic invasion of both the optic nerves by a non-detectable primary tumor.

摘要

一名68岁男性亚急性起病，出现双侧视力丧失，无其他神经学体征。磁共振成像显示脑室周围白质有一些散在的小T2高信号。脑脊液分析发现单核细胞增多及寡克隆γ带。静脉注射皮质类固醇治疗无效。临床情况恶化，患者死于支气管肺炎。尸检发现双侧视神经有明显的转移瘤侵犯，但未检测到原发肿瘤。