Minetti G, Low P S
Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Curr Opin Hematol. 1997 Mar;4(2):116-21. doi: 10.1097/00062752-199704020-00007.
Human erythrocytes are equipped with a diversity of receptors and effectors that mediate well-characterized signal transduction pathways in nonerythroid cells. Some of these erythrocyte components may be vestiges of signaling pathways critical to the functions of the erythrocyte's precursors but no longer needed in the mature erythrocyte. Other signaling elements, however, are likely involved in enabling the erythrocyte to detect and respond to the needs of other hematopoietic and endothelial cells with which it comes in contact.
人类红细胞配备了多种受体和效应器，这些受体和效应器介导非红细胞中特征明确的信号转导途径。其中一些红细胞成分可能是对红细胞前体细胞功能至关重要的信号通路的遗迹，但在成熟红细胞中不再需要。然而，其他信号元件可能参与使红细胞能够检测并响应与其接触的其他造血细胞和内皮细胞的需求。
