Perugini R A, Orr R K, Porter D, Dumas E M, Maini B S
Department of Surgery, Fallon Healthcare System, Worcester, USA.
Arch Surg. 1997 Apr;132(4):352-7. doi: 10.1001/archsurg.1997.01430280026003.
To determine preoperative and perioperative risk factors for gastrointestinal (GI) complications following cardiac surgery.
A database including records of patients who underwent cardiac surgery was reviewed, with univariate analysis of several variables thought to be relevant to GI complications. Using a risk-adjusted model, preoperative stratification was used to fit a logistic regression model including operative features.
All patients undergoing cardiac surgery from January 1, 1991, to December 31, 1994, at a university-affiliated teaching hospital.
Incidence of GI complications, postoperative mortality, length of hospital stay, and relative risk of GI complications based on multivariate analyses.
Gastrointestinal complications occurred in 2.1% of patients and had an associated mortality of 19.4%; this was higher than the mortality in patients without GI complications (4.1%; P < .001). Length of hospital stay was significantly longer in patients with GI complications (43 vs 13.4 days; P < .001). In patients who underwent coronary artery bypass grafting only, cardiopulmonary bypass time was significantly longer in patients with GI complications (166 vs 138 minutes; P = .004). In patients who underwent valve replacement, bypass time was not associated with GI complications. Use of a left internal mammary artery graft was associated with a lower incidence of GI complications.
Patients who have GI complications after cardiac surgery have a higher mortality and a longer hospital stay. The use of a left internal mammary artery seems to have a protective effect against GI complications. Based on these observations, patients may be stratified into low-, medium-, and high-risk groups.
确定心脏手术后胃肠道(GI)并发症的术前及围手术期危险因素。
回顾一个包含接受心脏手术患者记录的数据库,对几个被认为与GI并发症相关的变量进行单因素分析。使用风险调整模型,术前分层用于拟合一个包含手术特征的逻辑回归模型。
1991年1月1日至1994年12月31日在一所大学附属医院接受心脏手术的所有患者。
基于多因素分析的GI并发症发生率、术后死亡率、住院时间及GI并发症的相对风险。
2.1%的患者发生了胃肠道并发症,相关死亡率为19.4%;这高于无GI并发症患者的死亡率(4.1%;P <.001)。GI并发症患者的住院时间显著更长(43天对13.4天;P <.001)。仅接受冠状动脉旁路移植术的患者中,GI并发症患者的体外循环时间显著更长(166分钟对138分钟;P =.004)。接受瓣膜置换术的患者中,体外循环时间与GI并发症无关。使用左乳内动脉移植与GI并发症发生率较低相关。
心脏手术后发生GI并发症的患者死亡率更高,住院时间更长。使用左乳内动脉似乎对GI并发症有保护作用。基于这些观察结果,可将患者分为低、中、高风险组。