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100例头颈部表皮样癌患者的卡介苗辅助免疫治疗结果

Results of BCG adjuvant immunotherapy in 100 patients with epidermoid carcinoma of the head and neck.

作者信息

Suen J Y, Richman S P, Livingston R B, Hersh E M, Craig R, Tonymon K

出版信息

Am J Surg. 1977 Oct;134(4):474-8. doi: 10.1016/0002-9610(77)90381-6.

DOI:10.1016/0002-9610(77)90381-6
PMID:911030
Abstract

One hundred patients with advanced, recurrent, or metastatic squamous cell carcinoma of the head and neck were treated with chemotherapy and BCG as adjuvant immunotherapy. The overall response rate was 35 per cent, and the median duration of response was seventeen weeks. BCG does not prolong duration of remission or survival time.

摘要

100例晚期、复发性或转移性头颈部鳞状细胞癌患者接受了化疗，并辅以卡介苗免疫治疗。总体缓解率为35%，中位缓解持续时间为17周。卡介苗并不能延长缓解期或生存时间。

相似文献

1
Results of BCG adjuvant immunotherapy in 100 patients with epidermoid carcinoma of the head and neck.100例头颈部表皮样癌患者的卡介苗辅助免疫治疗结果
Am J Surg. 1977 Oct;134(4):474-8. doi: 10.1016/0002-9610(77)90381-6.
2
Chemotherapy versus chemoimmunotherapy of head and neck cancer: report of a randomized study.头颈部癌的化疗与化疗免疫疗法：一项随机研究报告
Cancer Treat Rep. 1976 May;60(5):535-9.
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A controlled study of combined methotrexate, BCG, and INH therapy for squamous cell carcinoma of the head and neck.甲氨蝶呤、卡介苗和异烟肼联合治疗头颈部鳞状细胞癌的对照研究。
Surg Clin North Am. 1977 Aug;57(4):769-78. doi: 10.1016/s0039-6109(16)41287-9.
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A randomized trial of adjuvant BCG immunotherapy in head and neck cancer.头颈部癌辅助卡介苗免疫疗法的一项随机试验。
Arch Otolaryngol. 1983 Aug;109(8):544-9. doi: 10.1001/archotol.1983.00800220050013.
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Toxicities of systemic agents in squamous cell carcinoma of the head and neck (SCCHN); A new perspective in the era of immunotherapy.头颈部鳞状细胞癌（SCCHN）中全身用药的毒性；免疫治疗时代的新视角。
Crit Rev Oncol Hematol. 2017 Jul;115:50-58. doi: 10.1016/j.critrevonc.2017.04.011. Epub 2017 Apr 27.
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Immune reactivity in head and neck squamous carcinoma and relevance to the design of immunotherapy trials.头颈部鳞状细胞癌中的免疫反应性及其与免疫治疗试验设计的相关性。
Semin Oncol. 1977 Dec;4(4):431-9.
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High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.高剂量甲氨蝶呤联合或不联合卡介苗治疗晚期头颈恶性肿瘤。
Cancer. 1979 Mar;43(3):1095-100. doi: 10.1002/1097-0142(197903)43:3<1095::aid-cncr2820430347>3.0.co;2-p.
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The controversial role of BCG in the treatment of squamous cell carcinoma of the head and neck.卡介苗在头颈部鳞状细胞癌治疗中的争议性作用。
Arch Otolaryngol. 1983 Aug;109(8):543. doi: 10.1001/archotol.1983.00800220049012.
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Response to docetaxel and cisplatin induction chemotherapy of locally advanced head and neck squamous cell carcinoma: a multicenter, non-comparative, open-label interventional pilot study.多西他赛和顺铂诱导化疗对局部晚期头颈部鳞状细胞癌的疗效：一项多中心、非对照、开放标签的介入性初步研究。
J Laryngol Otol. 2016 Sep;130(9):833-42. doi: 10.1017/S0022215116008513. Epub 2016 Jul 26.
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[Intratumor immunotherapy with BCG cell wall preparations: development of a new therapy approach for head-neck tumors].
Arch Otorhinolaryngol. 1982;236(3):245-55. doi: 10.1007/BF00454216.

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