Dowman R, Zimmer D
Department of Psychology, Clarkson University, Potsdam, New York 13699-5825, USA.
Somatosens Mot Res. 1996;13(3-4):255-62. doi: 10.3109/08990229609052581.
Painful heat produced an increase in the perceived magnitude of an innocuous electrical stimulus applied either to the sural nerve or to the skin of the dorsum of the foot. The increased sensitivity was observed when the painful heat was spatially coincident with the electrical stimulus, and when it was not coincident but adjacent within the same dermatome. Painful heat had no effect when it was applied to the contralateral foot, which makes it unlikely that attention or arousal played any role in the increased electrical sensitivity produced by ipsilateral heat. The painful heat also produced an increase in the amplitude of the sural nerve compound action potential (CAP). The heat-pain-related changes in the CAP and subjective magnitude ratings were in the same direction, which suggests that the latter were due at least in part to a temperature-dependent change in the electrical sensitivity of the peripheral afferents.
疼痛性热刺激会使施加于腓肠神经或足背皮肤的无害电刺激的感知强度增加。当疼痛性热刺激与电刺激在空间上重合时，以及当它们在同一皮节内不重合但相邻时，均观察到敏感性增加。当将疼痛性热刺激施加于对侧足部时则没有效果，这使得注意力或觉醒不太可能在同侧热刺激引起的电敏感性增加中发挥任何作用。疼痛性热刺激还会使腓肠神经复合动作电位（CAP）的幅度增加。CAP中与热痛相关的变化和主观强度评级变化方向相同，这表明后者至少部分是由于外周传入神经电敏感性的温度依赖性变化所致。
