Pedrozo M de F, Siqueira M E
Instituto Médico Legal de São Paulo, Brasil.
Rev Saude Publica. 1996 Jun;30(3):261-6. doi: 10.1590/s0034-89101996000300009.
Some chlorinated hydrocarbon solvents--1,1,1-trichloroethane, trichloroethylene and perchloroethylene--have a common biotransformation product, trichloroacetic acid, which can be used as their biological exposure index. The spectrophotometric and gas chromatographic methods for the determination of trichloroacetic acid were studied and used as well as in its determination in the urine of workers exposed to 1,1,1-trichloroethane. Both methods showed good precision and no statistically significant difference was found although the gas chromatographic method presented a lower detection limit.
一些氯代烃溶剂——1,1,1-三氯乙烷、三氯乙烯和全氯乙烯——有一个共同的生物转化产物三氯乙酸，它可用作它们的生物暴露指标。研究了测定三氯乙酸的分光光度法和气相色谱法，并将其用于测定接触1,1,1-三氯乙烷的工人尿液中的三氯乙酸。两种方法都显示出良好的精密度，尽管气相色谱法的检测限较低，但未发现统计学上的显著差异。
