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[抗生素所致过敏性休克的诊断]

[Diagnosis of anaphylactic shock caused by antibiotics].

作者信息

Donchenko V S, Lopatin A S

出版信息

Antibiotiki. 1977 Sep;22(9):816-21.

PMID:911153
Abstract

A total of 277 cases with anaphylactic shock due to the use of various antibiotics were analyzed. Anaphylactic shock due to penicillin (38.2 per cent), streptomycin (19.8 per cent), combihation of streptomycin with penicillin (16.9 per cent) or bicillin (15.2 per cent) was most frequent. The causes of the diagnostic mistakes are shown and the clinical signs of the main typical form of the drug anaphylactic shock are descrifed. Four variants of atypical clinical picture of anaphylactic shock, i.e. hemodynamic (collaptoid), asphyctic, cerebral and abdominal were classified. Examples of diagnostic mistakes are presented. It was shown that the drug allergological anamnesis was not always considered in the therapeutic practice.

摘要

对总共277例因使用各种抗生素而发生过敏性休克的病例进行了分析。因青霉素(38.2%)、链霉素(19.8%)、链霉素与青霉素联合使用(16.9%)或苄星青霉素(15.2%)导致的过敏性休克最为常见。文中展示了诊断错误的原因,并描述了药物过敏性休克主要典型形式的临床症状。对过敏性休克非典型临床表现的四种变体,即血流动力学型(类虚脱型)、窒息型、脑型和腹型进行了分类。列举了诊断错误的实例。结果表明,治疗实践中并非总是考虑药物过敏史。

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