Setoguchi M, Fujishima Y, Abe I, Kobayashi K, Fujishima M
Second Department of Internal Medicine, Kyushu University, Faculty of Medicine, Fukuoka, Japan.
Angiology. 1997 Apr;48(4):359-64. doi: 10.1177/000331979704800410.
Aortoiliac occlusion due to atherosclerosis is known to occur in elderly people. Two unique cases are documented here in which aortoiliac occlusion was observed in young men. These patients had no identifiable risk factors for developing atherosclerotic thrombosis except for the lupus anticoagulant, an immunoglobulin associated with thromboembolic episodes. Although previously the lupus anticoagulant has been reported to cause thrombosis only in relatively small-sized arteries or veins, it may also be associated with aortoiliac atheromatous occlusion in young men.
已知动脉粥样硬化导致的主髂动脉闭塞多见于老年人。本文记录了两例独特病例，均为年轻男性发生主髂动脉闭塞。除狼疮抗凝物（一种与血栓栓塞事件相关的免疫球蛋白）外，这些患者没有其他可识别的动脉粥样硬化血栓形成风险因素。尽管此前有报道称狼疮抗凝物仅在相对较小的动脉或静脉中导致血栓形成，但它也可能与年轻男性的主髂动脉粥样硬化闭塞有关。
