[Antibiotic strategy in bronchial infections. Role of roxithromycin].

UNLABELLED

BRONCHIAL SUPERINFECTIONS: Macrolides are first-line antibiotics for acute bronchitis and infectious complications of chronic bronchitis.

PROVEN EFFICACY

Data in the literature on roxithromycin treatment in respiratory tract infections demonstrate to clinical and bacteriological efficacy at high doses comparable with other available antibiotics. ANTIBIOTIC STRATEGY: These results are explained by the bioavailability of roxithromycin, its antibacterial spectrum, and its pharmacokinetic features (high serum peak, high intracellular and extracellular concentrations).