Gaillat J
Service de Médecine Interne, Centre Hospitalier de la Région Annecéenne, Annecy.
Presse Med. 1997 Mar;26 Suppl 2:16-21.
BRONCHIAL SUPERINFECTIONS: Macrolides are first-line antibiotics for acute bronchitis and infectious complications of chronic bronchitis.
Data in the literature on roxithromycin treatment in respiratory tract infections demonstrate to clinical and bacteriological efficacy at high doses comparable with other available antibiotics. ANTIBIOTIC STRATEGY: These results are explained by the bioavailability of roxithromycin, its antibacterial spectrum, and its pharmacokinetic features (high serum peak, high intracellular and extracellular concentrations).
支气管感染：大环内酯类药物是急性支气管炎和慢性支气管炎感染性并发症的一线抗生素。
关于罗红霉素治疗呼吸道感染的文献数据表明，高剂量时其在临床和细菌学方面的疗效与其他现有抗生素相当。抗生素策略：罗红霉素的生物利用度、抗菌谱及其药代动力学特征（高血清峰浓度、高细胞内和细胞外浓度）解释了这些结果。
