Hasin D, Van Rossem R, McCloud S, Endicott J
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Alcohol Clin Exp Res. 1997 Apr;21(2):213-9.
Despite the widespread influence of the alcohol dependence syndrome concept on the major nosological classification systems, little work has been done to test the validity of the alcohol dependence syndrome in community samples. In addition, numerous questions have been asked about the validity of current definitions of alcohol abuse. We examined the cross-sectional validity of DSM-IV alcohol dependence and abuse in 936 household residents randomly selected and screened for elevated drinking. We investigated validity by testing the association of a set of seven "criterion" variables, external to the alcohol diagnostic criteria, with dependence and abuse diagnoses. Results indicated that dependence diagnoses were significantly associated with all criterion variables when compared to those with no diagnosis, even though all subjects had elevated drinking and the cases of alcohol dependence were mild. In contrast, abuse diagnoses did not show a pattern of association with the criterion variables when compared to no diagnosis. When associations were tested comparing dependence cases to those with abuse only, results were mixed. This study is one in a series of investigations in this sample of household residents screened for elevated drinking levels.
尽管酒精依赖综合征概念对主要疾病分类系统具有广泛影响，但在社区样本中检验酒精依赖综合征有效性的工作做得很少。此外，人们对当前酒精滥用定义的有效性提出了诸多疑问。我们对936名随机选取并经筛查饮酒量偏高的住户居民进行了研究，以检验《精神疾病诊断与统计手册》第四版（DSM-IV）中酒精依赖和酒精滥用诊断标准的横向效度。我们通过测试一组七个在酒精诊断标准之外的“标准”变量与依赖和滥用诊断之间的关联来研究效度。结果表明，与未被诊断的人相比，依赖诊断与所有标准变量均显著相关，尽管所有受试者饮酒量都偏高且酒精依赖案例症状较轻。相比之下，与未被诊断的情况相比，滥用诊断并未呈现出与标准变量相关的模式。当比较依赖案例与仅存在滥用情况的案例之间的关联时，结果不一。本研究是对该饮酒量偏高的住户居民样本进行的一系列调查之一。
