Gregorini L, Marco J, Bernies M, Cassagneau B, Pomidossi G, Anguissola G B, Fajadet J
Clinique Posteur, Unité de Cardiologie Interventionelle, Toulouse, France.
Am J Cardiol. 1997 Apr 15;79(8):1100-3. doi: 10.1016/s0002-9149(97)00053-2.
Calcium antagonist pretreatment and intracoronary high doses of nitrates (9 mg of isosorbide dinitrate) do not counteract coronary vasoconstriction occurring after rotational atherectomy. In 30 patients undergoing Rotablator atherectomy, intracoronary injection of the alpha 1-sympathetic blocker urapidil abolished or prevented significant vasoconstriction occurring 15 minutes after the procedure despite repeated injections of nitrates.
钙拮抗剂预处理和冠状动脉内高剂量硝酸盐（9毫克硝酸异山梨酯）不能抵消旋磨术后发生的冠状动脉血管收缩。在30例行旋磨术的患者中，冠状动脉内注射α1-交感神经阻滞剂乌拉地尔可消除或预防术后15分钟出现的明显血管收缩，尽管已多次注射硝酸盐。
