MacGowan G A, Mann D L, Kormos R L, Feldman A M, Murali S
Division of Cardiology, University of Pittsburgh Medical Center, Pennsylvania 15213, USA.
Am J Cardiol. 1997 Apr 15;79(8):1128-31. doi: 10.1016/s0002-9149(96)00063-x.
In a group of patients with New York Heart Association class IV heart failure, significant relations between interleukin-6 and tumor necrosis factor-alpha, and between levels of both interleukin-6 and tumor necrosis factor-alpha and plasma levels of norepinephrine were observed. The present study also demonstrates that in patients with heart failure, elevated levels of tumor necrosis factor-alpha and interleukin-6 may be present even without cachexia.
在一组纽约心脏协会IV级心力衰竭患者中，观察到白细胞介素-6与肿瘤坏死因子-α之间以及白细胞介素-6和肿瘤坏死因子-α水平与去甲肾上腺素血浆水平之间存在显著相关性。本研究还表明，在心力衰竭患者中，即使没有恶病质，也可能存在肿瘤坏死因子-α和白细胞介素-6水平升高的情况。
