Takeda K, Kanno K, Minami T, Katsurada K
No To Shinkei. 1977 Jun;29(6):639-45.
Twenty two cases of the cervical and thoracic cord injury were studied to determine hemodynamic and respiratory function within 7 days from the injury. Most patients showed a tendency of bradycardia and hypotension on admission which were more remarkable in the group of lower cervical cord or the upper thoracic cord lesion than the upper cervical cord group. Such a hypotension and bradycardia tended to recover within 7 days. In cervical cord injury, cardiac output remained unchanged, which indicated that initial hypotension was due to decreased total peripheral resistance. Respiratory rate was slightly increased in most patients, but did'nt show any significant difference among the level of the lesion. PaO2 and PaCO2 were within normal range on admission, however PaO2 decreased gradually in 7 days only in cervical cord injury. Increased pulmonary arterial pressure was confirmed during the above hypoxemic period. It suggests that disturbance of neurological control of pulmonary circulation might play a significant role in the respiratory insufficiency of cervical cord injury.
对22例颈髓和胸髓损伤患者进行了研究，以确定损伤后7天内的血流动力学和呼吸功能。大多数患者入院时表现出心动过缓和低血压倾向，在下颈髓或上胸髓损伤组中比上颈髓损伤组更明显。这种低血压和心动过缓倾向于在7天内恢复。在颈髓损伤中，心输出量保持不变，这表明最初的低血压是由于总外周阻力降低所致。大多数患者的呼吸频率略有增加，但在损伤水平之间没有显示出任何显著差异。入院时动脉血氧分压（PaO2）和动脉血二氧化碳分压（PaCO2）在正常范围内，然而仅在颈髓损伤患者中，PaO2在7天内逐渐下降。在上述低氧期证实肺动脉压升高。这表明肺循环神经控制紊乱可能在颈髓损伤的呼吸功能不全中起重要作用。
