Chakrabarti K B, Doughty D, Plowman P N
Department of Radiotherapy/Oncology, St Bartholomew's Hospital, West Smithfield, London, UK.
Br J Neurosurg. 1996 Dec;10(6):577-83. doi: 10.1080/02688699646899.
We report our early experience using stereotactic radiotherapy (radiosurgery) in the treatment of cranial neuroma, by the linear accelerator method. We report the first 13 neuromas treated in 12 patients (follow-up 6-60 months). Radiologically, seven of 10 patients demonstrated signs of central tumour necrosis on follow-up scanning and four of these also demonstrated shrinkage. Of seven assessable acoustic neuroma patients treated, hearing was stabilized in three and improved in two. An abducent neuroma patient treated by this method is reported and demonstrated good response. Our preliminary studies endorse the opinion that stereotactic radiosurgery is a suitable and safe alternative to microsurgical procedures in the management of many cranial neuromas. Indications for stereotactic radiosurgery are discussed.
我们报告了使用直线加速器立体定向放射治疗（放射外科）治疗颅神经瘤的早期经验。我们报告了12例患者中首批治疗的13例神经瘤（随访6至60个月）。放射学检查显示，10例患者中有7例在随访扫描中出现肿瘤中心坏死迹象，其中4例还出现肿瘤缩小。在接受治疗的7例可评估的听神经瘤患者中，3例听力稳定，2例听力改善。报告了1例采用该方法治疗的外展神经瘤患者，显示出良好疗效。我们的初步研究支持以下观点：在许多颅神经瘤的治疗中，立体定向放射外科是显微外科手术的一种合适且安全的替代方法。文中还讨论了立体定向放射外科的适应证。
