Lister R K, Black M M, Calonje E, Burnand K G
Department of Surgery, St Thomas' Hospital, London, UK.
Br J Dermatol. 1997 Mar;136(3):384-7.
Two patients are reported in whom a squamous cell carcinoma arose in chronic lymphoedematous skin on the lower legs. Although lymphangiosarcoma is a well recognized complication of chronic lymphoedema, squamous cell carcinoma has only been reported on seven previous occasions. The pathogenesis of malignant tumours in chronic lymphoedema is discussed.